Enzymes

Commercial enzymes of the highest quality

Benefit from the combination of innovation and expertise when deploying commercial enzymes optimized to your requirements. OEM by QIAGEN offers bulk manufacturing of a wide variety of enzymes for diverse molecular applications. We draw on decades of experience, resources, and expertise to provide commercial enzymes with unique features and adjusted filling volumes and concentrations to meet your specifications. We are proud to be a leading OEM bulk enzyme supplier to major NGS solution providers worldwide.

Broad commercial enzyme portfolio overview

Consolidating your OEM supplier can be a challenge. OEM by QIAGEN is your one-stop-shop OEM manufacturer for commercial enzymes. We supply enzymes for various applications, including DNA polymerase, RNA polymerase, reverse transcription, ligases, PCR and RT-PCR master mixes.
Get a clear overview of our bulk enzyme manufacturing and customization capabilities by reviewing our interactive brochure.

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Bulk enzyme manufacturing capabilities

From the OEM enzyme portfolio

Types of enzymes	Applications (examples)	Products (examples)
DNA polymerases	qPCR, multiplex PCR, high fidelity PCR, GC-rich PCR, isothermal amplification, Next Generation Sequencing (NGS)	QuantiNova DNA Polymerase, Phoenix Hot-start Taq Polymerase, Taq-B DNA Polymerase, VeraSeq High-Fidelity DNA Polymerase, VeraSeq Ultra DNA Polymerase, Bst X DNA Polymerase, Phi29 DNA Polymerase
RNA polymerases	In-vitro mRNA synthesis, RNA therapeutics	T7 RNA Polymerase, Poly(A) Polymerase
Reverse transcriptases	cDNA synthesis, RT-PCR, one-step qRT-PCR	OmniScript, Sensiscript, EnzScript^™, M-MuLV Reverse Transcriptase, HotStaRT-Script
Ligases, DNA modifying enzymes-endo/ exonucleases, glycosylases, Lyases	Cloning, restriction digest, NGS library prep, DNA repair prior to PCR	T4 DNA Ligase, T4 RNA Ligase 1, BamHI, Bglll, Dpnl, Eagl, EcoRI, EcoRV, Exonuclease I, Ill and Lambda Exonuclease
Binding proteins	Primer sequestering, enhancing cDNA synthesis, mutagenesis or affinity capture of cDNA	E. coli Single-Stranded DNA Binding Protein, T4 Gene 32 Protein, RecA
Other enzymes and enzyme mix	DNA/RNA seq, DNA library prep, single cell RNAseq or SMART-type of RNAseq, NGS adapter ligation, 3' end labeling, phosphorylation of 5' ends prior to ligation	5X ER/A Tailing Enzyme Mix, WGS Ligase, 5X WGS Fragmentation Mix, Terminal Deoxynucleotidyl Transferase, T4 Polynucleotide Kinase

Custom enzyme portfolio

Take a further look at customizing capabilities of OEM enzymes in bulk.

Lyophilization

OEM by QIAGEN offers lyophilized enzymes customized to your needs. The lyophilization process of freeze-drying, extends shelf life and enables transport and storage at ambient temperature. We offer various formulations of glycerol-free, lyo-ready or lyophilized commercial enzymes and master mixes for diverse molecular biology applications.

Take a deeper look at our enzyme portfolio.

Multi-column purification

The purification process can include up to eight columns, achieving the utmost purity for downstream applications. We supply GMP-grade ISO compliant enzymes, produced as solution, lyophilized, lyo-ready, or glycerol-free formulations.

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Allow OEM by QIAGEN to be your trusted partner in making the correct "make or buy" decisions.

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REACH compliance

The initiative REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) of the European Union is relevant to any Life Science or MDx companies who want to sell their products on the European market. The initiative aims to regulate and limit the usage and disposal of “Substances of Very High Concern” (SVHC). Detergents widely used in the molecular biology industry are included in the European Authorization list (Annex XIV). Therefore their use is highly regulated. QIAGEN works with its OEM partners to ensure REACH compliance by adapting formulations and assuring supply according to strict quality standards.

Compliant, certified facilities

ISO and GMP certified manufacturing facilities, in Hilden, Germany and Beverly, USA, provide you with access to our broad range of commercial enzymes (off-the-shelf, bulk-ready and customized). With excellent QC and manufacturing experience, we deliver your OEM enzymes exactly where you need them.

Quality assurance